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<article article-type="research-article" dtd-version="1.3" xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xml:lang="ru"><front><journal-meta><journal-id journal-id-type="publisher-id">ilvm</journal-id><journal-title-group><journal-title xml:lang="ru">Нормативно-правовое регулирование в ветеринарии</journal-title><trans-title-group xml:lang="en"><trans-title>Legal regulation in veterinary medicine</trans-title></trans-title-group></journal-title-group><issn pub-type="ppub">2782-6252</issn><publisher><publisher-name>SpbGUVM Publishing House</publisher-name></publisher></journal-meta><article-meta><article-id custom-type="elpub" pub-id-type="custom">ilvm-103</article-id><article-categories><subj-group subj-group-type="heading"><subject>Research Article</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="ru"><subject>ИНВАЗИОННЫЕ БОЛЕЗНИ</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="en"><subject>INVASIVE DISEASES</subject></subj-group></article-categories><title-group><article-title>Эффективность вакцинации и применения пробиотика против эймериоза кур</article-title><trans-title-group xml:lang="en"><trans-title>Efficacy of vaccination and probiotic application against eimeriosis of chicken</trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Титова</surname><given-names>Т. Г.</given-names></name><name name-style="western" xml:lang="en"><surname>Titova</surname><given-names>T. G.</given-names></name></name-alternatives><email xlink:type="simple">noemail@neicon.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Бирюков</surname><given-names>И. М.</given-names></name><name name-style="western" xml:lang="en"><surname>Biryukov</surname><given-names>I. M.</given-names></name></name-alternatives><email xlink:type="simple">noemail@neicon.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Курочкин</surname><given-names>А. А.</given-names></name><name name-style="western" xml:lang="en"><surname>Kurochkin</surname><given-names>A. A.</given-names></name></name-alternatives><email xlink:type="simple">noemail@neicon.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Разбицкий</surname><given-names>В. М.</given-names></name><name name-style="western" xml:lang="en"><surname>Razbitskiy</surname><given-names>V. M.</given-names></name></name-alternatives><email xlink:type="simple">noemail@neicon.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Симонова</surname><given-names>Е. А.</given-names></name><name name-style="western" xml:lang="en"><surname>Simonova</surname><given-names>Ye. A.</given-names></name></name-alternatives><email xlink:type="simple">noemail@neicon.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Скрипка</surname><given-names>И. В.</given-names></name><name name-style="western" xml:lang="en"><surname>Skripka</surname><given-names>I. V.</given-names></name></name-alternatives><email xlink:type="simple">noemail@neicon.ru</email><xref ref-type="aff" rid="aff-2"/></contrib></contrib-group><aff-alternatives id="aff-1"><aff xml:lang="ru"><institution>Всероссийский научно-исследовательский ветеринарный институт птицеводства - филиал Федерального государственного бюджетного научного учреждения Федерального научного центра «Всероссийский научно-исследовательский и технологический институт птицеводства» Российской академии наук</institution><country>Россия</country></aff><aff xml:lang="en"><institution>The All-Russian Scientific Research Veterinary Institute of Poultry Breeding - a branch of the Federal State Budgetary Scientific Institution of the Federal Scientific Center "All-Russian Scientific Research and Technological Institute of Poultry" of the Russian Academy of Sciences</institution><country>Russian Federation</country></aff></aff-alternatives><aff-alternatives id="aff-2"><aff xml:lang="ru"><institution>Группа компаний «ВИК»</institution><country>Россия</country></aff><aff xml:lang="en"><institution>Group of companies "VIC"</institution><country>Russian Federation</country></aff></aff-alternatives><pub-date pub-type="collection"><year>2018</year></pub-date><pub-date pub-type="epub"><day>16</day><month>12</month><year>2021</year></pub-date><volume>0</volume><issue>3</issue><fpage>65</fpage><lpage>67</lpage><permissions><copyright-statement>Copyright &amp;#x00A9; Титова Т.Г., Бирюков И.М., Курочкин А.А., Разбицкий В.М., Симонова Е.А., Скрипка И.В., 2021</copyright-statement><copyright-year>2021</copyright-year><copyright-holder xml:lang="ru">Титова Т.Г., Бирюков И.М., Курочкин А.А., Разбицкий В.М., Симонова Е.А., Скрипка И.В.</copyright-holder><copyright-holder xml:lang="en">Titova T.G., Biryukov I.M., Kurochkin A.A., Razbitskiy V.M., Simonova Y.A., Skripka I.V.</copyright-holder><license xml:lang="ru" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>Данная работа распространяется под лицензией Creative Commons Attribution 4.0.</license-p></license><license xml:lang="en" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>This work is licensed under a Creative Commons Attribution 4.0 License.</license-p></license></permissions><self-uri xlink:href="https://ilvm.elpub.ru/jour/article/view/103">https://ilvm.elpub.ru/jour/article/view/103</self-uri><abstract><p>В настоящей работе приводятся продуктивные показатели цыплят-бройлеров после двукратной вакцинации методом с кормом смесью аттенуированных штаммов Л-2-15 E. acervulina в дозе 3000 ооцист/гол., Л-3-2 E. maxima в дозе 500 ооцист/гол. и Л-1-23 E. tenella в дозе 1000 ооцист/гол с одновременной дачей препарата на основе дрожжей Saccharomyces cerevisiae тип boulardii (I-1079) не менее 2х109 КОЕ/г. Цыплят-бройлеров разделили на группы: иммунная группа, иммунная группа с пробиотиком, контрольная группа заражения, контрольная группа заражения с пробиотиком, контрольная чистая группа и контрольная чистая группа с пробиотиком, по 9 голов в каждой. Через двадцать одни сутки после начала вакцинации птицу иммунных групп и контрольных групп заражали смесью полевых культур эймерий E. acervulina в дозе 1,91 млн. ооцист/гол., E. maxima в дозе 0,01 млн. ооцист/гол. и E. tenella в дозе 0,29 млн. ооцист/гол, выделенной из птицеводческого хозяйства РФ. За птицей наблюдали в течение десяти суток после заражения, учитывали продуктивные показатели цыплят-бройлеров и процент выживаемости по группам. Статистически достоверные различия получены в значениях среднесуточного прироста живой массы цыплят-бройлеров в контрольных группах и контрольных группах с пробиотиком. Снижение среднесуточного прироста живой массы наблюдали в группах контрольной зараженной и контрольной заражённой с пробиотиком после заражения смесью полевых культур эймерий. Процент выживаемости в группе контрольной заражённой составлял 88,9 %. В иммунной группе и иммунной группе с пробиотиком гибели цыплят-бройлеров не наблюдали.</p></abstract><trans-abstract xml:lang="en"><p>In this paper, the productive indicators of broiler chickens are given after a double vaccination with the feed method with a mixture of attenuated strains L-2-15 E. acervulina at a dose of 3000 oocysts / head, L-3-2 E. maxima at a dose of 500 oocysts/head and L-1-23 E. tenella at a dose of 1,000 oocysts/head with concurrent administration of a preparation based on yeast Saccharomyces cerevisiae type boulardii (I-1079) not less than 2 x 109 CFU/g. Chicken broilers were divided into groups: immune group, immune group with probiotic, control group of infection, control group of infection with probiotic, control native group and control native group with probiotic, 9 heads each. Twenty one days after the start of vaccination, the bird of immune groups and control groups was infected with a mixture field cultures of E. acervulina at a dose of 1,91 million oocysts/ head, E.maxima at a dose of 0,01 million oocysts/ head and E. tenella at a dose of 0,29 million oocysts/ head, isolated from the Russian poultry industry. The bird was observed for ten days after infection, taking into account the productive parameters of broiler chickens and the percentage of survival by groups. Statistically significant differences were obtained in the mean daily growth in the live weight of broiler chickens in control groups and control groups with a probiotic. Decrease in the average daily gain of live weight was observed in the groups of control infected and control infected with probiotic after infection with a mixture of field cultures of Eimeria. The survival rate in the control group is 88,9 %. In the immune group and the immune group with probiotic, broiler chickens were not observed to die.</p></trans-abstract><kwd-group xml:lang="ru"><kwd>эймериоз</kwd><kwd>Eimeria</kwd><kwd>аттенуированные штаммы</kwd><kwd>иммунизация</kwd><kwd>пробиотик</kwd><kwd>цыплята -бройлеры</kwd><kwd>прирост живой массы</kwd><kwd>выживаемость</kwd><kwd>ecoccidiosis</kwd><kwd>Eimeria</kwd><kwd>attenuated strains</kwd><kwd>immunization</kwd><kwd>probiotic</kwd><kwd>chicken broiler</kwd><kwd>body weight gain</kwd><kwd>survival</kwd></kwd-group></article-meta></front><back><ref-list><title>References</title><ref id="cit1"><label>1</label><citation-alternatives><mixed-citation xml:lang="ru">Abu-Akkada, S.S. 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