Energy deficit, caused by low feed palatability and increased milk synthesis, leads to the activation of alternative energy replenishment pathways from the body's own reserves (Evglevsky A. A. et al., 2011; Kharitonov E. L. et al., 2024). This results in the development of various widespread diseases, such as ketosis, osteodystrophy, acidosis, hepatosis, and others. To replenish energy deficit and restore appetite in cows after calving, and to prevent the occurrence of energy deficit, acidosis, ketosis, and reduced milk production, the product "KETOMILK ENERGY," manufactured by OOO IP "APEXPLUS," was developed and tested.It was established that when this premix was administered orally, compared to propylene glycol, the incidence of cow diseases decreased: parturient paresis by 3 times, rumen hypotonia by 2.6 times, retained placenta by 2.3 times, fatty liver dystrophy by 1.7 times, and acute endometritis by 39.6%. A reduction in the service period duration was observed in cows, from an average of 106 days in the control group to 82 days in the experimental group. On the 24th day, gastrointestinal disorders in newborn calves were at the same level in both the experimental and control groups.