Susceptibility of Salmonella Typhimurium, isolated from poultry, to antimicrobials

Abstract

For the sake of the research we isolated 10 strains of S. Typhimurium from poultry with salmonellosis and then we assessed susceptibility of the 10 strains of S. Typhimurium to a number of antimicrobials, using disk diffusion susceptibility test. The data we obtained showed that fluoroquinolones above all boast high activity against most of the studied isolates. All of the strains proved susceptible to enrofloxacin, ciprofloxacin and levofloxacin. Ofloxacin and moxifloxacin retained high activity against 90% of the strains. One isolate (10%) appeared resistant to both of them. As many as 50 % of the isolated strains proved resistant to norfloxacin. While reviewing the data we had obtained for aminoglycoside antibiotics we determined that all of the recovered strains were susceptible to netilmicin and neomycin but one isolate (10%) proved resistant to tobramycin and kanamycin. And the data we had obtained for susceptibility of Salmonella to penicillin antibiotics showed that 90% of the strains were susceptible to amoxycillin and 80% were susceptible to аmoxicillin/clavulanic acid. The data for cephalosporin antibiotics prove that cefotaxime was active against 100% of the strains. As many as 90% and 80% of the strains were susceptible to cefoxitin and ceftazidime respectively. It is worth noting that only 30% of the strains were susceptible to cefazolin. All of the strains appeared resistant to mac rolide antibiotics (namely tylosin and tilmicosin). We also studied the 10 strains as for their susceptibility to other groups of antibiotics. We marked that all the strains were susceptible to florfenicol. As many as 80 % to 90 % of the isolated Salmonella strains were susceptible to meropenem, doxycycline and colistin. Remarkably high level of resistance of the 10 bacterial strains was determined for co-trimoxazole (90 %). We also noted that 30 % of the studied isolates were multidrug-resistant (MDR) bacteria.