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The role of clinical and laboratory tests in the diagnosis of chronic renal failure in dogs

https://doi.org/ 10.17238/issn2072-6023.2018.4.129

Abstract

Kidney disease among pets, including dogs, have enough common pathology and annually in many kennels dog of Russia. Diagnosis at nephrological patients, as well as determination of the severity of the inflammatory process, its nature, evaluating the effectiveness of the therapy is impossible without ascertaining the laboratory-clinical picture of the patient's urine and blood of the animal. When clinical examination of dogs with suspected chronic kidney failure has been found that the disease was manifested in the form of oligofagii varying degrees of symptoms from selectivity in choosing the feed supplied to anorexia. There was apathy and weakness forced supine position, rapid fatigability, with various physical loads, stiffness, and standing often noted bulging back. Sometimes the present phenomenon of vomiting. Increased body temperature, tachycardia, dyspnea, anemichnost mucous membranes. When laboratory urinalysis sick dogs marked proteinuria and lejkocitourija, as well as increasing the number of epithelial cells. In the study of blood of experimental animals was marked leucocytosis, increased erythrocyte sedimentation rate, neutrophilia with shift of the nucleus to the right, lowering the amount of hemoglobin. When the biochemical study of blood dogs noted increase in the number of total protein globulinova protein fraction, raise, raising urea, urea, residual nitrogen nitrogen and creatinine. Content in the blood serum of experimental dogs General biliru-Bina, alkaline phosphatase, alanine aminotransferase (Alat) and aspartataminotransferazy (Asat) before therapeutic measures were also promoted. Thus, clinical and laboratory studies have shown that in the body of dogs with signs of chronic renal-sufficiency not occur deep destructive changes, vozhdaemye resistance change in the clinical laboratory indicators in the urine and blood of animals. Laboratory urine and blood of dogs with signs of chronic renal failure to diagnose this pathology in the early stages of development, that facilitates the therapeutic and preventive measures.

About the Authors

S. P. Kovalyov
St. Petersburg State Academy of Veterinary Medicine
Russian Federation


P. S. Kiselenko
St. Petersburg State Academy of Veterinary Medicine
Russian Federation


V. N. Gaponova
St. Petersburg State Academy of Veterinary Medicine
Russian Federation


V. A. Trushkin
St. Petersburg State Academy of Veterinary Medicine
Russian Federation


A. A. Nikitina
St. Petersburg State Academy of Veterinary Medicine
Russian Federation


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Review

For citations:


Kovalyov S.P., Kiselenko P.S., Gaponova V.N., Trushkin V.A., Nikitina A.A. The role of clinical and laboratory tests in the diagnosis of chronic renal failure in dogs. Legal regulation in veterinary medicine. 2018;(4):129-132. (In Russ.) https://doi.org/ 10.17238/issn2072-6023.2018.4.129

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