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Pathogenetic aspects of the development of the immune deficiency condition of the cattle in the industrial territories

https://doi.org/ 10.17238/issn2072-6023.2018.4.255

Abstract

Historically, agriculture complexes in the Ural region are located near enterprises black and non-ferrous metallurgy. Moreover, the concentration of industrial facilities in this region is the largest in Russian federation. When are agriculture enterprises placing on industrial territories it leads to chronically influence an organism animal. Chemical, physical and another factors a significant change of animal health. With short-term exposure or low concentrations of man-made factors in the body, compensatory processes develop, so that there are no changes in clinical condition and productivity. Further deterioration of the environmental situation causes the development of immunosuppression, metabolic disorders, allergic conditions. An immuno-hematological study of cows 5-6 years old, calves of 30 days and 6 months of age was carried out. It has been established that the development of secondary immunodeficiency occurs at all stages of ontogenesis in industrial territories. Hemoglobin of cow’s levels decreased by 27.1 %, erythrocytes - by 17.9% compared with the average regional values, phagocytic activity was 48%, while the phagocytic index was 4.87. In calves of 30 days of age, the number of erythrocytes was lower by 15%, the hemoglobin content - by 12.3%, the number of T-lymphocytes by 1.8 times, and B-lymphocytes - by 2.3 times. By 6 months of age, the number of eosinophils and monocytes increases significantly in calves, which may be due to the antigenic load during vaccination. The adverse effect of environmental factors is accompanied by a reduction in humoral and stimulation of the cellular defense mechanisms of the body: inhibition of hematopoiesis, lymphocytopenia.

About the Authors

I. A. Shkuratova
FSBSI «Ural Federal Agrarian Scientific Research Centre, Ural Branch of the Russian Academy of Science»
Russian Federation


M. V. Ryaposova
FSBSI «Ural Federal Agrarian Scientific Research Centre, Ural Branch of the Russian Academy of Science»
Russian Federation


O. V. Sokolova
FSBSI «Ural Federal Agrarian Scientific Research Centre, Ural Branch of the Russian Academy of Science»
Russian Federation


A. I. Belousov
FSBSI «Ural Federal Agrarian Scientific Research Centre, Ural Branch of the Russian Academy of Science»
Russian Federation


N. A. Vereshchak
FSBSI «Ural Federal Agrarian Scientific Research Centre, Ural Branch of the Russian Academy of Science»
Russian Federation


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Review

For citations:


Shkuratova I.A., Ryaposova M.V., Sokolova O.V., Belousov A.I., Vereshchak N.A. Pathogenetic aspects of the development of the immune deficiency condition of the cattle in the industrial territories. Legal regulation in veterinary medicine. 2018;(4):255-258. (In Russ.) https://doi.org/ 10.17238/issn2072-6023.2018.4.255

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