Efficacy of a combined antibiotic based on doxycycline and tilosine in pigs enterococcosis

Abstract

In order to improve treatment and prophylactic measures for bacterial etiology diseases of pigs the combined antibiotic Tildox was developed in the form of a powder. One gram of drag contains 100 mg of doxycycline hydrochloride and 100 mg of tylosin tartrate as active ingredients.
The aim of our research was to study the efficacy of Tildox in the treatment of enterococcal infection in piglets.
For the experiment 3 groups of 50 piglets of the rearing group were formed with a pre-established diagnosis of enterococcal infection. The study drug was administered orally at a dose of 1 g per 1 L of drinking water which corresponds to 100 mg of the drug (10 mg of doxycycline and 10 mg of tylosin) per 1 kg of animal body weight once a day. The animals of the first group were injected with the drug for 3 days, the animals of the second group were given the drug for 5 days. Animals of group 3 served as control - they were orally administered a third-party preparation based on doxycycline according to the instructions at a dose of 10 mg / kg of doxycycline once a day for 5 days. The diagnosis - enterococcal infection of piglets was confirmed by the method of bacteriological research. For this feces were collected from animals in the studied sectors. Diagnostics was carried out before the start of the experiment as well as immediately after the end of the experiment.
As a result of the research the following was established. The use of an antibiotic based on doxycycline and tylosin at a dose of 10 mg / kg for each active ingredient once a day for 5 days is the most effective way to treat piglets suffering from enterococcosis.