Chronic renal failure in aged cats changes in hematological parameters and evaluation of the effectiveness of treatment in small veterinary clinics

Abstract

The article presents the results of hematological studies in aged cats with chronic renal insufficiency. The aim is to study changes in hematological parameters in aged cats with chronic renal failure and to evaluate the effectiveness of treatment in small veterinary clinics. The studies were performed on sick animals belonging to private owners (n=24). A total of 66 samples of blood and blood serum were examined. Clinical and hematological studies were carried out according to methods generally accepted in veterinary practice.

Unidirectional changes in the level of red blood indicators were revealed in aged cats, which is associated with the depletion of compensatory capabilities of the red bone marrow. In the blood serum of age-related patients, the content of nitrogenous products (total protein, urea, creatinine) was increased, indicating the fourth stage of renal dysfunction on the IRIS scale. Thus, in aged animals with chronic renal insufficiency syndrome, a decrease in the rate of hematopoiesis and glomerular filtration of the kidneys, a tendency to hepatopathy, osseopathy and changes in the elemental composition of the internal environment of the body were established. The treatment was carried out with the transfer to the Renal series feed and the improvement of the drinking regime

Etiotropic therapy included oral administration of sinulox at the rate of 12.5 mg / kg of body weight, twice a day, for 5- 7 days. Substitution treatment included intravenous administration of saline solution. Symptomatic treatment consisted of intramuscular administration of pyridoxine and cyancobalamin, oral use of the drug "bio-iron" in courses of 10 procedures.

Two patients died. The 15 out of 22 cats showed an improvement in clinical indicators and an increase in body weight. The use of treatment of age-related patients with symptoms of stage IV chronic renal failure for 10 days allowed to stimulate appetite, improve diuresis and thirst, stop inflammatory processes in the body and support hematopoiesis, reduce the level of nitrogen-containing metabolites. But it is impossible to achieve a complete restoration of the functional activity of all organs.