Analysis of drugs for treatment of endometritis in cows

Abstract

Obstetric and gynecological diseases in cows, including endometritis, are one of the main obstetric and gynecological problems in animal husbandry. To date, the incidence rate of cows with endometritis of various etiologies is quite high and amounts to 37.5%. The arsenal of drugs used in veterinary obstetrics, gynecology, andrology and reproductive technologies is constantly growing and expanding. In recent decades, new veterinary drugs have appeared on the drug market, which are used in clinical practice to regulate reproductive function and for therapeutic purposes in domestic and wild animals. When analyzing registered veterinary drugs against animal endometritis, it showed that most of them are domestic drugs (83%), and the rest are foreign (17%). Of all drugs, the group of antibacterial drugs accounts for 44.4%: 25% of which can be attributed to the group of macrolides; 25% of the group of quinolones and fluoroquinolones; 12.5% belongs to the group of cephalosporins; 12.5% belongs to the tetracycline group; 12.5% refers to the group of aminoglycosides in combinations; 6.25% belongs to the group of penicillins; 6.25% other antibacterial drugs. A less extensive group of drugs against endometritis are antiseptic - 22.2%. Of these, 37.5% are based on iodine. Antihypoxants and antioxidants, vitamins and vitaminlike substances account for 5.6% of the total number of medicines. 22.2% includes drugs of different pharmacological groups. When analyzing the dosage forms used in the treatment of endometritis in cows, the following results were obtained: the share of liquid dosage forms for intrauterine administration accounted for 44.5%, liquid dosage forms for parenteral use 30.6%, solid dosage forms accounted for 11.1%, soft dosage forms 13.8%. A large group of drugs for the treatment of endometritis are antibacterial drugs, the choice of which is quite justified.