Prospects for using the drug based on melanin in treatment of dogs and cats with ureline disease

Abstract

The problem of urolithiasis and urostasis is widespread among small domestic animals (cats, dogs, etc.). Despite the introduction of new methods of treatment, diagnosis and prevention, attention to this pathology is growing every year. The main factors of this pathology are: an imbalance in the diet for protein and phosphorus, early castration, reduced activity, housing with insufficient walking or its complete absence, bacterial infections of the urinary system, etc. lead to the occurrence of urolithiasis among small domestic animals. This pathology is chronic, and in the absence of treatment and late contact of the owners to the veterinarian, it can result in serious complications (uremia, renal failure) and, in some cases, death of the animal. Given the severity of this problem, the search for new methods of treatment and prevention of urolithiasis is an urgent task. Even surgery does not solve this problem. As a result of external lithotripsy, there is a risk of recurrence and complications. Removal of uroliths from the urinary tract is not a guarantee of complete recovery. In order to reduce the re-formation of uroliths, complex preventive measures are carried out, including the elimination of causes. In our study, we studied the effect of the drug Melavit, containing buckwheat melanin as an active component, in the treatment of dogs and cats diagnosed with urolithiasis. It has been noted that melavite, when administered orally to dogs and cats, resulted in a reduction in the formation of urocystoliths such as struvite and mixed calculi.