Caseous lymphadenitis in sheep and goats semiotics and the experience of struggle
https://doi.org/10.52419/issn2782-6252.2024.3.47
Abstract
Based on the analysis of the research experience of various scientists in recent years, this article describes both the characteristic and non-specific pattern of the manifestation of caseous lymphadenitis, possible methods of combating epizootics, including through active immunization of animals. Existing data do not sufficiently disclose the pathogenesis and can be used for preliminary diagnosis, and control methods developed during many years of research and testing do not always effectively solve the problem of epizootics, which is due, among other things, to the lack of vaccines.
Keywords
caseous lymphadenitis,
vaccination,
analysis,
semiotics,
adjuvant,
antigen,
immunization,
epizootics
About the Authors
N. V. Pimenov
Moscow State Academy of Veterinary Medicine and Biotechnology named after K.I. Scriabin
Russian Federation
Russian Federation
Nikolay V. Pimenov, Dr.Habil. of Biological Sciences, Professor
H. A. Almuslimavi
Moscow State Academy of Veterinary Medicine and Biotechnology named after K.I. Scriabin
Russian Federation
Russian Federation
Almuslimavi Hassan Abdulwahab M. D., PhD student
R. F. Ivannikova
Moscow State Academy of Veterinary Medicine and Biotechnology named after K.I. Scriabin
Russian Federation
Russian Federation
Regina F. Ivannikova, PhD of Biological Sciences, Docent
References
1. Kudryashov, A.A. Pathoanatomic changes in caseous lymphadenitis of goats / A.A. Kudryashov, V.A. Kuzmin, A.V. Zabrovskaya, V.I. Balabanova // Current issues of veterinary biology. – 2015. – № 4(28). – Pp. 73-78. – EDN VBEWAV.
2. Kuzmin, V.A. Pseudotuberculosis. Infectious diseases of animals [Text] / V.A. Kuzmin, Yu.Yu. Danko, T.M. Kindras; edited by A.A. Kudryashov, A.V. Svyatkovsky. – St. Petersburg: Lan, 2007. – pp. 96-100.
3. Bastos B.L., Portela R.W.D., Dorella F.A., Ribeiro D., Seyffert N., (2012) Corynebacterium pseudotuberculosis: immunological responses in animal models and zoonotic potential. J Clin Cell Immunol 01:1–15. https://doi.org/10.4172/2155-9899.S4-005.
4. Christensen D. (2016) Vaccine adjuvants: why and how. Hum Vaccin Immunother 12:2709–2711. https://doi.org/10.1080/21645515.2016.121900.
5. Faccioli-Martins P.Y., Alves F.S.F., Pinheiro R.R. (2014) Linfadenite Caseosa: perspectivas no diagnóstico, tratamento e controle. EMBRAPA Doc Online 113.
6. Gerdts V., Wilson H.L., Meurens F., Van den Hurk S. van D.L., Wilson D., Walker S., Wheler C., Townsend H., Potter A.A. (2015) Large animal models for vaccine development and testing. ILAR J.56:53–62 https://doi.org/10.1093/ilar/ilv009.
7. Hobernik D., Bros M. (2018) DNA Vaccines – How Far from Clinical Use ? 1–28. https://doi.org/10.3390/ijms19113605.
8. Leal K.S., de Oliveira Silva M.T., de Fátima Silva Rezende A., Bezerra F.S.B., Begnini K., Seixas F., Collares T., Dellagostin O., Portela R.W., de Carvalho Azevedo V.A., Borsuk S. (2018) Recombinant M. bovis BCG expressing the PLD protein promotes survival in mice challenged with a C. pseudotuberculosis virulent strain. Vaccine 36:3578–3583 https://doi.org/10.1016/j.vaccine.2018.05.049.
9. Moyle P.M., Toth I. (2013) Modern subunit vaccines: development, components, and research opportunities. 1– 18. https://doi.org/10.1002/cmdc.201200487.
10. Rezende A.F.S., Brum A.A., Bezerra F.S.B., Braite D.C., Sá G.L., Thurow H.S., Seixas F.K., Azevedo V.A.C., Portela R.W., Borsuk S. (2020) Assessment of the acid phosphatase CP01850 from Corynebacterium pseudotuberculosis in DNA and subunit vaccine formulations against caseous lymphadenitis.BrazVet72:199–207.
11. Rezende A.F.S., Brum A.A., Reis C.G., Angelo H.R., Leal K.S., Silva M.T.O., Simionatto S., Azevedo V., Santos A.R., Portela R.W., Dellagostin O., Borsuk S. (2016) In silico identification of Corynebacterium pseudotuberculosis antigenic targets and application in immunodiagnosis. J Med Microbiol 65:521–529.
12. Ribeiro D., Rocha F.D.S., Morais K., Leite C., Soares S.D.C., Silva A., Wagner R., Portela D., Meyer R., Miyoshi A., Oliveira S.C., Azevedo V., Dorella F.A. (2014) An iron-acquisition-deficient mutant of Corynebacterium pseudotuberculosis efficiently protects mice against challenge.Vet Res 45(1):1–6.
13. Selim S.A., Ghoneim M.E., Mohamed K.F. (2010) Vacinal efficacy of genetically inactivated phospholipase D against caseous lymphadenitis in small ruminants. Int J Microbiol Res 1(3):129–136.
14. Silva M.T.D.O., Bezerra F.SB., de Pinho R.B., Begnini K.R., Seixas F.K., Collares T., Portela R.D., Azevedo V., Dellagostin O., Borsuk S. (2018) Association of Corynebacterium pseudotuberculosis recombinant proteins rCP09720 or rCP01850 with rPLD as immunogens in caseous lymphadenitis immunoprophylaxis. Vaccine 36:74–83.https://doi.org/10.1016/j.vaccine.2017.11.029.
15. Silva M.T.O., Pinho R.B., Bezerra FSB, Campos V.F., Azevedo V., Borsuk S. (2019) Establishment of an objective endpoint in mice model for caseous lymphadenitis vaccine trials. Vet Microbiol 230:86–89. https://doi.org/10.1016/j.vetmic.2019.01.017.
16. Windsor P.A., Bush R.D. (2016) Caseous lymphadenitis: present and near forgotten from persistent vaccination? Small Rumin Res 142:6–10. https://doi.org/10.1016/j.smallrumres.2016.03.023.
17. Windsor P.A. (2011) Control of caseous lymphadenitis. Vet Clin N Am Food Anim Pract 27:193–202. https://doi.org/10.1016/j.cvfa.2010.10.019.
18. Windsor P. (2014) Managing control programs for ovine caseous lymphadenitis and paratuberculosis in Australia, and the need for persistent vaccination. Vet Med Res Rep 11. https://doi.org/10.2147/vmrr.s44814.
19. Young J.R., Evans-Kocinski S., Bush R.D., Windsor P.A. (2015) Improving smallholder farmer biosecurity in the Mekong region through change management. Transbound Emerg Dis 62:491–504.https://doi.org/10.1111/ tbed.12181
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For citations:
Pimenov N.V., Almuslimavi H.A., Ivannikova R.F. Caseous lymphadenitis in sheep and goats semiotics and the experience of struggle. Legal regulation in veterinary medicine. 2024;(3):47-50. (In Russ.) https://doi.org/10.52419/issn2782-6252.2024.3.47
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