Evaluation of the effect of some treatment regimens of dry cows with genital Mycoplasmosis on the protein metabolism of their offspring

Abstract

Modern political realities force us to rely on the development of our own agricultural production in order to ensure the country's food independence. To achieve this goal, it is necessary to increase its production while increasing profitability. In industrial animal husbandry, the main reserve for the implementation of this task is to reduce the incidence of animals and obtain healthy offspring from them. In this regard, the development of inexpensive and effective ways of diagnosing treatment becomes relevant. This is of the greatest importance for a group of diseases characterized by a long latent period and erased symptoms, which include genital mycoplasmosis of cattle. The purpose of the research was to study the use of the antibacterial drug tulatromycin and its combination with the immunomodulator thymalin in pregnant cows with genital mycoplasma on the protein metabolism of their calves. To conduct the experiment, three experimental groups of calves from cows with genital mycoplasmosis were formed, calves from clinically healthy animals served as controls. The total protein, protein fractions, classes of immunoglobulins and their proportion in the globulin fraction were determined in all groups. During the experiment, it was found that calves from infected cows have pronounced dysproteinemia. The use of tulathromycin for the treatment of cows leads to a partial restoration of the content of immunoglobulins in their offspring, whereas the combination of both tulathromycin and thymalin applied to pregnant cows ensures the restoration of all studied indicators in calves born by them to the level of their healthy peers.