The use of vaccines for the prevention and treatment of dermatomycosis in small domestic animals (retrospective analysis)

The authors present information about the effective of the use of local national vaccines against microsporia and trichophytia of dogs and cats for therapeutic and preventive purposes. The research work was carried out on base of the veterinary clinic «Vettal» in Moscow from 2013 to 2023. During the analyzed period veterinarians carried out 2,065 animal vaccinations against microsporia and trichophytia. Of these 1,263 dogs and cats were vaccinated for preventive purposes and 802 animals were vaccinated for therapeutic purposes, which are overwhelmingly represented by cats. The diagnosis of dermatomycosis was established on the basis of examination, laboratory and instrumental diagnostics. The phase contrast method microscopy was used for pathological material for the convenience of identifying pathogens of fungal diseases. For therapeutic purposes vaccination was carried out 2 or 3 times. The intervals between administration of the drugs were 10- 14 days. The evaluation criteria recovered animals were: absence of clinical manifestations on the body, negative luminescent diagnosis, repeated mycological sowing on nutrient media without growth of the pathogen. According to the results of the analysis, the authors found that after 2-fold vaccination of animals diagnosed with microsporia/trichophytia, recovery occurred in 66.32% of sick cats and 87.27% of sick dogs; after 3-fold vaccination, recovery occurred in 84.71% of cats and 95.45% of dogs. According to the results of a survey of doctors with more than ten years of experience and accounting documents, 100% effectiveness of preventive vaccination of cats and dogs with domestic antifungal vaccines has been established, subject to compliance with the vaccination regime. Thus carrying out preventive and curative vaccinations in dogs and cats with local national specialized vaccines against microsporia and trichophytia is a highly effective and safe method of combating eooanthroponous dermatomycosis.

1. Galimova A.R. Experience in treating feline microsporia / A.R. Galimova, I.R. Gatiyatullin // Innovative development of productive and unproductive animal husbandry: Collection of scientific papers of the international scientific and practical conference. - Bryansk: Bryansk State Agrarian University. - 2022. - P. 61-64.

2. Karibaeva A.T. Modern features of the clinic, epidemiology, immune mechanisms of trichophytosis, microsporia and improvement of therapy: author's abstract. diss. doctor of medical sciences / A.T. Karibaeva. - Almaty. - 2010. - P. 40.

3. Koshlyak V.V. Forms of the course, age dynamics, features of diagnosis and treatment of canine trichophytosis / V.V. Koshlyak // International research journal. - 2021. - No. 8 (110).

4. Kuznetsov A.F. Veterinary mycology / teaching aid for universities / Moscow: Yurait Publishing House, 2024. - P. 345.

5. Ovchinnikov R.S. Asymptomatic mycocarriage and its importance in the spread of dermatophytosis in animals and humans / R.S. Ovchinnikov, M.G. Manoyan, A.G. Gainullina // Vetpharma, 2012. - No. 3.

6. Ovchinnikov R.S. Mycological screening of domestic animals is an important way to prevent human dermatophytosis / R.S. Ovchinnikov, P.P. Ershov, A.V. Kapustin, V.A. Savinov, A.G. Gainullina // Advances in Medical Mycology. - 2019. - P. 712-716.

7. Skogoreva A.M. Comparison of the effectiveness of two treatment regimens for microsporia in cats / A.M. Skogoreva, E.S. Klimkina // Modern problems of general and applied parasitology: Collection of scientific articles based on the materials of the XVI national scientific and practical conference in memory of professor V.A. Romashov. - Voronezh. - 2022. - P. 169-173.

8. Tugunova T.B. Clinical, epizootological and etiological features of the manifestation of dermatomycosis in dogs and cats in a large city, improving treatment regimens for cats with microsporia: author's abstract. diss. can. veterinary sciences / T.B. Tugunova. Novosibirsk. - 2004. - P. 143.

9. Khanis A.Yu., Gafurova A.M., Semenov I.V. Zooanthroponotic microsporia. "Vetzverocenter" (electronic publication) URL: http://vetzverocenter.ru/images/companies/1/data2017/files/Зооантропонознаямикория.pdf1501066328828