Phytobiotic preparations for the prevention of eimeriosis in birds as an alternative to coccidiostatics
https://doi.org/10.52419/issn2782-6252.2025.1.80
Abstract
Avian eimeriosis is a widespread disease caused by various types of coccidia, to which almost all young poultry are susceptible. The disease is characterized by damage to the mucous membrane of the gastrointestinal tract, impaired parietal digestion and, as a result, a decrease in the absorption of nutrients from the feed. Aimeriosis is a significant problem in poultry farms, as it can cause massive losses among livestock and significantly reduce the productivity of birds. The main means of preventing and treating coccidiosis in broilers are coccidiostatics, but scientists note that with prolonged courses of treatment, coccidia adapt to the negative factors of chemoprophylaxis and acquire resistance to coccidiostatics, which leads to a decrease in the effectiveness of this treatment.
Today, the issue of the need to use biologically active substances of plant origin, known as phytobiotics, as a preventive measure for avian eimeriosis is becoming increasingly relevant. The attention of many researchers is attracted by plants of the genus Thymus, whose representatives are sources of medicinal raw materials of natural origin, which have a fairly wide range of effects. Thyme-based phytobiotics can become an alternative to coccidiostatics due to their anti-inflammatory, antimicrobial and antiparasitic properties. The use of thyme extract, in addition to its antiparasitic effect, helps to increase the productivity of poultry: it improves physiological parameters, normalizes metabolism and increases feed conversion rate.
About the Authors
A. A. SavichevaRussian Federation
Alesya An. Savicheva - biotechnologist; postgraduate student
Saint Petersburg
S. A. Makavchik
Russian Federation
Svetlana An. Makavchik - Dr. of Veterinary Sciences, Assoc. Prof
Saint Petersburg
N. S. Patyukova
Russian Federation
Natalia S. Patyukova - Biotechnologist
Saint Petersburg
E. A. Brazhnik
Russian Federation
Evgeny Al. Brazhnik - Candidate of Agricultural Sciences, Quality Controller – Veterinarian
Saint Petersburg
References
1. Alekseenkova E. Coccidosis: prevention and treatment / Alekseenkova E. // Effective animal husbandry. 2020; 2(159). Access mode: https://cyberleninka.ru/article/n/koktsidoz-profilaktika-i-lechenie (date of access: 21.03.2025).
2. Biryukov I.M., Biryukova T.M. Structural features of the immune response of chickens in coccidiosis. Poultry farming. 2022;11: 73-81.
3. Bogdanova E. S. Comparative analysis of the fatty acid composition of various species of Thymus (Lamiaceae) / E. S. Bogdanova, V. M. Vasyukov, O. A. Rozentsvet // News of higher educational institutions. The Volga region. Natural sciences. 2023;1(41): 83-92.
4. Valentinov B.G., Sukhoi G.T., Volochaeva M.V. et al. Chemical composition of the chloroform extract of thyme herb (creeping thyme) (Thymus serpylluml., family Lamiaceae) (communication II). Bulletin of new Medical technologies. Electronic edition. 2021; Vol. 15. No. 6.: 63-70.
5. Duskaev G.K., Klimova T.A. Phytochemicals in poultry feeding: prospects for use (review). Animal husbandry and feed production. 2022; Vol. 105, No. 3: 137-152.
6. Israpilova A.I., Aliyev A.M., Adieva A.A. et al. Antibacterial effect of Savory extract (Satureja hortensis) in relation to strains of pure cultures of Escherichia coli, Salmonella spp. and Staphylococcus aureus. South of Russia: ecology, development. 2024;Vol. 19, No. 3(72): 116-123
7. Kishnyaikina E.A., Zhuchaev K.V., Bagno O.A., Tokarev V.S., Kochneva M.L., Lisunova L.I., Garth V.V. The effect of thyme extract on the quality of meat of broiler chickens. Innovations and food safety. 2019;2(24): 25-31.
8. Kubasova E.D., Krylov I.A., Korelskaya G.V., Pantyukhova K.A., Kubasov R.V. Antitumor and antiinflammatory properties of tannins of plant origin and prospects for their use in pharmacy. Health and education in the XXI century. 2022.
9. Mkrtchyan M.E., Sidorenko K.V., Zaikin V.A., Ilyin G.M. Features of localization of endocytic stages of chicken and rabbit eimeria in the mucous membrane of the small intestine. Modern problems of general and private parasitology: proceedings of the IV International Parasitological Symposium. Saint Petersburg. Saint Petersburg State University of Veterinary Medicine. 2022. pp. 164-166.
10. Nasonov I.V., Logvinov O.L. Comparative effectiveness of nonspecific and specific prevention of avian eimeriosis in a broiler poultry farm. Animal husbandry and veterinary medicine. 2021;2(41): 52-55.
11. Nesterova O.V., Revicheva V.V. Analysis of the range of herbal remedies for the treatment and prevention of helminthiasis. Scientific research: development vectors: Collection of materials of the II International Scientific and Practical Conference, Cheboksary, August 27, 2018. Cheboksary: Limited Liability Company "Center for Scientific Cooperation "Interactive plus". 2018.
12. Paliy A.E., Khlypenko L.A., Yezhov V.N., Vinogradov B.A. Comparative analysis of volatile compounds of essential oil and ethanol extract of thyme (Thymus striatus Vahl.). Collection of scientific papers of the Nikitsky State Botanical Garden. 2011; Vol. 133: 159-166.
13. Reznichenko L.V., Reznichenko A.A., Musienko V.V. New biologically active additives in broiler poultry farming. Current issues of agricultural biology. 2020; 3(17): 28-33.
14. Ryabtsev P.S., Biryukov I.M., Simonova E.A., Ilyin G.M. Nonspecific resistance in broiler chickens with eimeriosis with the combined use of salinomycin and beta-glucan. Poultry farming. 2022;7-8: 72-77.
15. Sidorenko K. V. The influence of the induced intensity of invasion by eimeria on the morphometric parameters of the large and small intestines of rabbits of different breeds. Current issues and solutions in veterinary medicine and animal husbandry: Collection of materials of the International Scientific and Practical Conference dedicated to the 90th anniversary of the birth of Professor Yu.F. Yudichev, Tyumen, May 26-28. 2021. Vol. 1. Tyumen: State Agrarian University of the Northern Urals. pp. 282-288.
16. Sizova E.A., Nechitailo K.S., Lebedev S.V. Phytobiotics as potential regulators of the functional activity of the intestinal microbiome in broiler chickens - a mini-review. Agricultural Biology. 2022; Vol. 57. No. 6: 1071-1082.
17. Trineeva O.V., Kolosova O.A., Verzunova D.R. Analysis of the range of herbal medicines based on thyme herb presented on the Russian pharmaceutical market. Bulletin of VSU, series: Chemistry. Biology. Pharmacy. 2024;4:136-144.
18. Shatskikh E.V., Korolkova-Subbotkina D.E. The state of the intestines of broiler chickens when a phytobiotic supplement is included in the diet. Agrarian Bulletin of the Urals. 2022;S14: 81-91.
19. Abu El Ezz N.M.T. Therapeutic effect of Moringa oleifera and Thymus vulgaris oils against hepatic coccidiosis in experimentally infected rabbits. Tropical Biomedicine. 2020;T.37.N4.:1018 -1028.
20. Belali M. Substantiable bioconversion of the aromatic plant extracts biomass as feed additives in broiler performance: effects and prefeasibility comparison of thyme (Thymus vulgaris). Biomass Conversion and Biorefinery. 2022. pp. 1-13.
21. Gholami-Ahangaran M., Ahmadi-Dastgerdi A., Azizi S., Basiratpour A., Zokaei M., Derakhshan M. Thymol and carvacrol supplementation in poultry health and performance. Vet Med Sci. 2022; Jan,8(1):267-288.
22. Jamroz D., Wertelecki T., Houszka M., Kamel C. Influence of diet type on the inclusion of plant origin active substances on morphological and histochemical characteristics of the stomach and jejunum walls in chicken. Journal of Animals Physiology and Animal Nutrition. 2006;90(5-6):255-268.
23. Khoshnejad A., Yakhehali M., Malekifard F. Effects of plant extracts of Camellia sinensis and Thymus vulgaris on sporulation of Eimeria oocysts of broiler exereta under laboratory conditions. Iranian Journal of Animal Science. 2023;T.54. N 1.:93-104.
24. Rahimi S. Effect of the three herbal extracts on growth performance, immune system, blood factors and intestinal selected bacterial population in broiler chickens. Journal of Agricultural Science and Technology. 2021;T.13. N4.:527-539.
Review
For citations:
Savicheva A.A., Makavchik S.A., Patyukova N.S., Brazhnik E.A. Phytobiotic preparations for the prevention of eimeriosis in birds as an alternative to coccidiostatics. Legal regulation in veterinary medicine. 2025;(1):80-85. (In Russ.) https://doi.org/10.52419/issn2782-6252.2025.1.80