Efficacy of Tulamycin - AVZ against mycoplasma pneumonia in pigs

Respiratory diseases of pigs cause great economic damage all over the world. Mycoplasma hyopneumoniae (M. hyopneumoniae) is actively involved in the development of respiratory diseases in pigs. It is quite difficult to isolate an animal from a pathogen, especially since the mechanism of the disease is very complex and not fully understood [4]. The clinical signs of the disease are more pronounced around the age of 18-20 weeks, which are characterized by a dry cough, sneezing, and developmental delay [5].
Improving management, maintenance and biosecurity practices allows us to control this infection. But even the most careful control cannot protect the pig population from respiratory diseases [2].
The use of antimicrobial drugs active against M. hyopneumoniae is an integral part of the occurrence of the disease.
The purpose of our tests was to determine the effectiveness of the drug Brulamycin-AVZ in porcine mycoplasma pneumonia. The experiment was conducted on 75 large white breed pigs. Animals of 19 weeks of age, with a live body weight of ± 45 kg. Two groups of pigs with obvious clinical signs of the disease were formed.
There were 25 animals in each group. The first group was experimental (sick animals), the second served as a control (sick animals) and the third control group (intact animals). Experimental group (sick animals) Tulamycin-AVZ was administered at a dose of 100 mg/ml once intramuscularly in the neck area at the rate of 1 ml per 40 kg of body weight (2.5 mg of tulatromycin per 1 kg of body weight). The second group (sick animals) and the third (intact animals) acted as controls and did not receive the drug.
Based on the data obtained, it can be concluded that the use of Tulamycin-AVZ once intramuscularly in the neck area at a dose of 1 ml per 40 kg of animal body weight gave a positive result in the dynamics of mycoplasma pneumonia. All the animals that received the drug recovered. There were no clinical signs of the disease. The DNA of Mycoplasma microorganisms was not detected in the studied samples of nasopharyngeal flushes, and no enterococcal culture was isolated.

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