Biotechnology in post -traumatic regeneration of bone tissue
https://doi.org/10.52419/issn2782-6252.2025.2.79
Abstract
Bone regeneration is a complex, well-organized physiological process of bone formation that can be observed during normal fracture healing and that participates in continuous remodeling throughout life. Bone has the potential for regeneration, which can best be seen by its repair after a fracture. Bone is capable of healing fractures or local defects with new tissue and regeneration without loss of high structural organization and scarring. Despite the fact that with reparative osteogenesis there are prerequisites for the complete restoration of bone structures to replace the lost ones, the percentage of complications after traumatic injuries remains quite high. This necessitates the development of new experimental and theoretical approaches to the problem of bone regeneration, including elucidating the biological mechanisms underlying the process of chemotaxis and cell differentiation in the area of traumatic injury, studying the formation of complex cellular and tissue components of the regenerate, the conditions under which this occurs, and the factors governing osteoreparation.
About the Authors
E. A. Smirnova
Moscow State Academy of Veterinary Medicine and Biotechnology – MBA named after K.I. Skryabin
Russian Federation
Russian Federation
Ekaterina Al. Smirnova - Cand. of Biological Sciences, Docent, Department of Immunology and Biotechnology
R. F. Ivannikova
Moscow State Academy of Veterinary Medicine and Biotechnology – MBA named after K.I. Skryabin
Russian Federation
Russian Federation
Regina F. Ivannikova - Cand. of Biological Sciences, Docent, Department of Physiology, Pharmacology and Toxicology
A. M. Lunegov
Saint Petersburg State University of Veterinary Medicine
Russian Federation
Russian Federation
Aleksandr M. Lunegov - Cand. of Veterinary Science, Docent, Head of the Department of Pharmacology and Toxicology
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Review
For citations:
Smirnova E.A., Ivannikova R.F., Lunegov A.M. Biotechnology in post -traumatic regeneration of bone tissue. Legal regulation in veterinary medicine. 2025;(2):79-83. (In Russ.) https://doi.org/10.52419/issn2782-6252.2025.2.79
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