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Signal proteins and steroid hormones as markers of inflammatory processes in the reproductive organs of sows

Abstract

The studies on the role of signal proteins and steroid hormones in the regulation of reproductive processes in sows in normal and pathological conditions were conducted on 20 sows included into the experiment on 110-112 days of pregnancy and on 3-4 days after farrowing divided into two groups depending on the nature of the postpartum period: the sows of the first group (n=10) were clinically healthy; the sows of the second group (n=10) were infected with endometritis and MMA. It was found that the sows with the risk of developing pathology in the reproductive organs observed the increase in the level of progesterone against the background of reduced content of estradiol-17β and cortisol with the activation of the synthesis of pro - and anti - inflammatory cytokines (before farrowing), in the postpartum period there was the increase in the level of progesterone and estradiol - 17β and the ratio of pro-and anti-inflammatory cytokines. During the resumption of sexual cycles the increase in cortisol, reducing the ratio of pro-and anti-inflammatory cytokines, indicators of which can serve as signal markers in the regulation of reproductive processes in sows in normal and pathological conditions were observed.

About the Authors

Yu. N. Brigadirov
SSI All-Russian research veterinary Institute of pathology, pharmacology and therapy of RAAS
Russian Federation


V. N. Kotsarev
SSI All-Russian research veterinary Institute of pathology, pharmacology and therapy of RAAS
Russian Federation


I. T. Shaposhnikov
SSI All-Russian research veterinary Institute of pathology, pharmacology and therapy of RAAS
Russian Federation


A. E. Lobanov
SSI All-Russian research veterinary Institute of pathology, pharmacology and therapy of RAAS
Russian Federation


V. I. Volkova
SSI All-Russian research veterinary Institute of pathology, pharmacology and therapy of RAAS
Russian Federation


K. O. Kopytina
SSI All-Russian research veterinary Institute of pathology, pharmacology and therapy of RAAS
Russian Federation


References

1. Важные гормоны во время беременности [Электронный ресурс]. Режим доступа: https:// flovit.ru/beremennost/diagnostika/gormon-beremennosti.html.

2. Кетлинский С.А. Цитокины. /С.А. Кетлинский, А.С. Симбирцев - СПб: ООО «Издательство Фолиант», 2008. - С. 391.

3. Коцарев В.Н. Деполен для профилактики метрит-мастит-агалактии у свиноматок /В.Н. Коцарев, В.Д. Мисайлов, В.С. Бузлама //Ветеринария. - 2005. - № 1. - С. 39-42.

4. Роль кортизола в организме [Электронный ресурс]. - Режим доступа: http://www.tiensmed.ru/ news/post_new2393.html.

5. Роль цитокинов в регуляции реакции воспалительного ответа [Электронный ресурс]. - Режим доступа: http://helpiks.org/1-83705.html.

6. Симбирцев А.С. Цитокины - новая система регуляции защитных реакций организма [Электронный ресурс] /А.С. Симбирцев //ГНЦ НИИ особо чистых биопрепаратов, Санкт-Петербург. -Режим доступа: http://betaleukin.ru/lib/24/26

7. Эстрадиол при беременности [Электронный ресурс]. Режим доступа:http://spuzom.com/ estradiol-pri-beremennosti. html.

8. [Электронный ресурс]. - Режим доступа: https://www.okd. ru/patient/it_important/doc/57.pdf

9. Osman I. Leukocyte density and proinflammatory cytokine expression in human fetal membranes, decidua, cervix and myometrium before and during labour at term /I. Osman, A. Young, M. Ledingham et al. //Molecular Human Reproduction. - 2003. - V.9. - P. 41-45.

10. Saji F. Cytokine production in chorioamnionitis / F. Saji, Y. Samejima, S. Kamiura et al. //Journal of Reproductive Immunology. - 2000. - V. 47. -P. 185-196.


Review

For citations:


Brigadirov Yu.N., Kotsarev V.N., Shaposhnikov I.T., Lobanov A.E., Volkova V.I., Kopytina K.O. Signal proteins and steroid hormones as markers of inflammatory processes in the reproductive organs of sows. Legal regulation in veterinary medicine. 2018;(3):71-73. (In Russ.)

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ISSN 2782-6252 (Print)