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Microbial contamination of milk and immunological parameters of clinically healthy lactating cows in the prevention of mastitis by bovine recombinant alpha and gamma interferons

Abstract

The article presents the materials of the studies on the effect of bovine recombinant α-and γ-interferons of 2.5 ml on microbiological and immunological parameters of milk of clinically healthy lactating cows. It was found that the monthly double treatment of lactating cows with bovine recombinant α - and γ-interferons at the intervals of 48 hours provided a preventive effect in 37.5% of the animals, reducing the number of the cow milk contaminated with microflora, and the degree of its contamination, as well as optimized immunological indicators of the udder secretion (lysozyme, total immune-globulins, CEC).

About the Authors

N. T. Klimov
All-Russian Research Veterinary Institute of Pathology, Pharmacology and Therapy of Russian Academy of Agricultural Sciences
Russian Federation


V. I. Zimnikov
All-Russian Research Veterinary Institute of Pathology, Pharmacology and Therapy of Russian Academy of Agricultural Sciences
Russian Federation


D. A. Erin
All-Russian Research Veterinary Institute of Pathology, Pharmacology and Therapy of Russian Academy of Agricultural Sciences
Russian Federation


A. V. Pashentsev
All-Russian Research Veterinary Institute of Pathology, Pharmacology and Therapy of Russian Academy of Agricultural Sciences
Russian Federation


O. A. Manzhurina
All-Russian Research Veterinary Institute of Pathology, Pharmacology and Therapy of Russian Academy of Agricultural Sciences
Russian Federation


Yu. S. Parkhomenko
All-Russian Research Veterinary Institute of Pathology, Pharmacology and Therapy of Russian Academy of Agricultural Sciences
Russian Federation


IS. . Chernyshova
All-Russian Research Veterinary Institute of Pathology, Pharmacology and Therapy of Russian Academy of Agricultural Sciences
Russian Federation


E. V. Tyurina
All-Russian Research Veterinary Institute of Pathology, Pharmacology and Therapy of Russian Academy of Agricultural Sciences
Russian Federation


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Review

For citations:


Klimov N.T., Zimnikov V.I., Erin D.A., Pashentsev A.V., Manzhurina O.A., Parkhomenko Yu.S., Chernyshova I., Tyurina E.V. Microbial contamination of milk and immunological parameters of clinically healthy lactating cows in the prevention of mastitis by bovine recombinant alpha and gamma interferons. Legal regulation in veterinary medicine. 2018;(3):74-77. (In Russ.)

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ISSN 2782-6252 (Print)