Morpho-biochemical indicators of blood of cows at different nature of the gestation course and the level of milk productivity

The article presents the materials of the research on the study of morphological, biochemical, immunological parameters of blood of cows with different nature of the first month of gestation and the level of milk productivity. It was found that with the increase of milk productivity in animals with complicated pregnancy (the syndrome of delayed embryo development and intrauterine death) there is an increase in the content of leukocytes by 20.4-46.6%, including eosinophils - by 28.9-56.8%, rod neutrophils - by 1.66-2.0 times, monocytes - by 11.8-26.5%, indicating the development of inflammatory reaction in pregnant animals. In these animals, there is a more intense increase in the level of total protein by 6.0-10.9%, urea - by 9.1-13.9%, creatinine - by 10.7-19.8%, with a decrease in glucose and total lipids by 5.9 and 5.8%, respectively, which leads to excessive accumulation of protein metabolism products, increased functional load on the liver and kidneys. In the cows predisposed to the development of the syndrome of delay and intrauterine death, the content of vitamin A reduced by 6.0-13.9% compared to the animals with normal gestation, vitamin E - by 6.4-24.1%, copper - by 9.9-12.8%, zinc - by 12.1-16.6%, manganese - by 3.1-6.5%, selenium - by 5.1-8.5% associated with iodine protein - by 4.7-7.4%.m especially in highly productive animals, reducing the viability of the embryo and its normal development. In 32-35 days of pregnancy, the highest concentration of progesterone was observed in animals with physiological gestation with milk production of 4000-5000 kg and is 54.6±2.9 nmol/l, and the lowest in highly productive cows -44.1±3.4 nmol/l, which is 23.8% less. In the cows with physiological course of gestation the concentration of progesterone at the end of the first month of gestation by 17.9% and 27.9% was higher than in the development of the syndrome of delayed development of the embryo and 45.1-60.1 per cent compared to the intrauterine death. Gestation in highly productive cows occurs on the background of low progesterone levels being the risk factor for embryopathy.

коровы, внутриутробная гибель, синдром задержки развития эмбриона, прогестерон, морфологические и биохимические показатели, cows, intrauterine death, syndrome of delayed embryo development, progesterone, morphological and biochemical parameters

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