Composition of immunocompetent cells and cellular structure of the mammary gland in mice in the phase of lactation and physiological rest

Abstract

White outbred mice at the age of 8 months, selected by the method of pairs-analogues, were used for the study. In this case group 1 - non lactating mice, group 2 - lactating. Histological preparation was prepared from the breast of mice in 1, 7, 14 days of pregnancy and on the first day of delivery. The sections were stained with hematoxilin-eosin. The duration of lactation at the time of the study was 7 days. In mice, the mammary gland was isolated, cut and made an imprint on the slide. The prepared preparations were dried and stained with Pappenheim and examined using immersion optics. Prior to pregnancy, rare galactophores channels to be and the accumulation of cells around them are found in the embryo. The morphological structure of the breast on the first day after birth, i.e. on the first day of the colostrum period, allows us to note the almost complete replacement of the glandular parenchymal connective fat tissue. The presence and composition of leukocytes in the mammary gland is directly dependent on the physiological state of the female. This humoral interaction is an important factor in the maintenance of the breast in a certain status, due to which the synthesis of colostrum and milk occurs in the alveoli.