Antibiotic resistance of microbiota of drinking milk sold in St.Petersburg and Leningrad region
https://doi.org/10.52419/issn2782-6252.2023.2.52
Abstract
In view of the increasing interest in the issues of antibiotic resistance of opportunistic microorganisms, there is a need for a closer study of bacteria isolated from animal products. Such bacteria can carry genes for resistance to antimicrobial drugs, including those used to treat human diseases [4, 10]. In this case, drinking milk is of particular interest, because the antibiotic-resistant bacteria contained in it can freely enter the body in the absence of additional heat treatment before consumption.
The work took into account the requirements of the Technical Regulations of the Customs Union (TR CU) 021/2011 "On food safety" and TR CU 033/2013 "On the safety of milk and dairy products", as well as the recommendations of the European Committee for Antimicrobial Susceptibility Testing EUCAST and the Interregional Association for clinical microbiology and antimicrobial chemotherapy MACMAC.
As a result of the research, the presence of resistance to antibacterial drugs was determined in 36 bacterial isolates from milk sold in St. Petersburg and the Leningrad Region. It was found that the most common resistance to ampicillin (24 cases) and tetracycline (6 resistant isolates, 8 with intermediate values). There were also cases of resistance and intermediate results of isolates in relation to other antibiotics, including cephalosporins.
About the Authors
A. E. Noskov
Institute of Biochemistry and Physiology of Microorganisms, G.K. Scriabin RAS
Russian Federation
Russian Federation
student
E. Ig. Prikhodko
St. Petersburg University of Veterinary Medicine
Russian Federation
Russian Federation
PhD of Veterinary Sciences, Docent
X. Dm. Martynova
St. Petersburg University of Veterinary Medicine
Russian Federation
Russian Federation
student
References
1. Batrakov A.Ya., Videnin V.N. Measures to prevent udder diseases in cows and improve the quality of milk // Veterinary pharmacological bulletin. 2017; 1:57-61.
2. Kulmagambetov I.R., Sarsenbayeva S.S., Ramazanova Sh.Kh., Esimova N.K. Modern approaches to the control and containment of antibiotic resistance in the world. Medical Sciences. 2015; 9:54-59.
3. Makavchik S.A. Hypermucoid phenotypes of Klebsiella pneumoniae and problems of antibiotic therapy in farm animals // Questions of legal regulation in veterinary medicine. 2019. No. 4.S. 48-51.
4. Makavchik, S.A. Laboratory methods for the control of multiresistant pathogens of bacterial animal diseases and the rational use of antimicrobial drugs: monograph Makavchik S.A., Sukhinin A.A., Engashev S.V., Krotova A.L. St. Petersburg, 2021.-152p.
5. Popov P.A. Residual content of veterinary drugs in milk in different countries. Problems of veterinary sanitation, hygiene and ecology. 2020; 2(34): 158-164.
6. Sulyan, O.S. Associated resistance to polymyxin and beta-lactams of Escherichia coli isolated from humans and animals / Sulyan O.S., Ageevets V.A., Sukhinin A.A., Ageevets I.V., Abgaryan S.R., Makavchik S. A., Kameneva O.A., Kosyakova K.G., Mrugova T.M., Popov D.A., Punchenko O.E., Sidorenko S.V.//Antibiotics and chemotherapy.- 2021.- T. 66.- No. 11-12.- S. 9-17.
7. Tatarnikova N.A., Maul O.G. Antibiotics in food. Biological Sciences. 2014; 5(49): 208-211.
8. Shitova M.A., Kondaleev G.N., Malovasty K.S. The quality of milk in the treatment of animals with antibiotics. Scientific problems of livestock production and improvement of its quality. 2014; 18-21.
9. Pantozzi F.L., Ibar M.P., Nievas V.F., Vigo G.B., Moredo F.A., Giacoboni G.I. Wild-type minimal inhibitory concentration distributions in bacteria of animal origin in Argentina. Revista Argentina de Microbiología. 2014; 46(1): 34-40.
10. Tillotson G.S., Zinner S.H. Burden of antimicrobial resistance in an era of decreasing susceptibility. Expert Review of Anti-infective Therapy. 2017; 15(7): 663-676.
Review
For citations:
Noskov A.E., Prikhodko E.I., Martynova X.D. Antibiotic resistance of microbiota of drinking milk sold in St.Petersburg and Leningrad region. Legal regulation in veterinary medicine. 2023;(2):52-56. (In Russ.) https://doi.org/10.52419/issn2782-6252.2023.2.52
Views:
120
Email this article 