The article analyzes normative documents applied in the customs territory of the Customs Union member countries in the field of ensuring the safety of poultry meat and processed products. It is established that the safety of poultry meat and products of its processing is ensured through technical regulation, the application on a voluntary basis of the standardization system, as well as veterinary and sanitary-epidemiological surveillance. The main provisions of the Technical Regulations of the Customs Union «On the Safety of Food Products» have been analyzed, the effect of which applies to objects of technical regulation - poultry meat and processed products until the adoption of the Technical Regulations of the Eurasian Economic Union «On the safety of poultry meat and processed products». National and interstate standards have been studied, the use of which on a voluntary basis ensures compliance with the requirements of the Technical Regulations of the Customs Union «On Food Safety». It is determined that in order to uniformly ensure the safety of poultry meat and processed products in the customs territory of the countries participating in the Customs Union, a HACCP system must be established and operate at enterprises.

Organizations and individuals or individual entrepreneurs, including foreign ones, carrying out on their own behalf production (manufacture), storage, disposal, destruction, movement (transportation) and sale of controlled goods must comply with mandatory requirements of the legislation of the Russian Federation in the field of veterinary medicine. In the article the order of systematization of obligatory requirements to managing subjects is considered. Reflected the need for changes in the regulatory legal framework that defines the requirements for supervised facilities. The Federal Service for Veterinary and Phytosanitary Surveillance carries out state control (supervision) in the field of veterinary medicine and in the sphere of circulation of medicinal products for veterinary use. Regulatory legal acts have been studied, compliance with which is assessed when conducting state control (supervision). The Federal Service makes, asserts, amends the list of legal acts and their separate parts (provisions) containing mandatory requirements, compliance with which is assessed when conducting state veterinary control (supervision). The list of adopted legal acts is available on the official website of the Federal Service for Veterinary and Phytosanitary Surveillance. Clarification of the content of mandatory requirements, subject to compliance with business entities, condributes to the prevention of violations of the legislation of the Russian Federation in the field of veterinary medicine. Methods of supporting business entities and facilitating business are the transition from an assessment of the effectiveness and effectiveness of the supervisory bodies, based on the number of violations detected and the amount of sanctions, to assess the extent of the damage prevented.

The subject of research is proposed in a 2017 edition of the draft Federal law "On the state control (supervision) and municipal control in the Russian Federation" developed by the Ministry of economic development and submitted by the Government of the Russian Federation in accordance with the instructions of the President of the Russian Federation. At the end of the year held a large-scale public and parliamentary hearings on discussion of the draft law. The draft law has been under development for several years. Significant innovations of the draft law are a closed list of types of state control (supervision) and municipal control, and the introduction in the control and supervision sector risk-oriented approach. The draft law, if adopted, will have a significant impact on many spheres of life and economy, including the sphere of food safety. The main conclusion of the study is that the bill has significant gaps and contradictions: inconsistency with other legal acts, the invalidity from a scientific point of view, the weak conceptual framework, many reference rules, the lack of elaboration about the amount of additional budget funding for the implementation of the provisions of the law, other problems. This could adversely affect the regulated social relations, including on the industry of agriculture and ensure the quality and safety of food products. The bill in question is in our opinion in need of additional revision and can not be adopted as proposed.

In duck farms, due to the concentration of poultry of different age in limited areas, there is a danger of an epizootic of viral hepatitis of type I ducklings, especially among newly imported livestock. The wide spread of the disease is due to the high resistance of the virus in the external environment, the persistent persistence of the recovered bird in the body, its genetic variability, and the stationary economy that is not safe. The paramount stage in the fight against infection in the breeding herds of ducks is the timely and correct diagnosis of the disease. The optimal conditions for the formation of an en zyme-linked immunoassay for detecting antibodies to the hepatitis virus of the Type I duckweed have been determined. The high sensitivity and specificity of ELISA in the study of homologous and heterologous blood sera are shown, in the absence of false positive or questionable results. Comparative evaluation of antibody titers in ELISA and RN showed a high correlation (r = -1,0) of their values. The immunoenzyme test system be can recommended for retrospective diagnosis and control of postvaccinal immunity level in this disease.

Rabies is one of the most dangerous and severe infectious diseases, characterized by the defeat of the central nervous system and remains to this day almost deadly for animals and humans. The aim of the work is to analyze the epizootic situation in rabies of wild and domestic carnivores in the Novgorod region and the Novgo-rod region in the period from 2008 to 2015. Laboratory diagnostics for rabies was carried out by the staff of the Novgorod Regional Veterinary Laboratory in accor-dance with the Instruction on measures to combat rabies of animals by microscopic examination of smears-prints of the brain for the detection of Babesh-Negri bodies, and the setting of bioassay on white mice - suckers or rabbits.Based on a compre-hensive study of epizootic features of rabies in the Novgorod region and the Novgorod region in the period 2008-2015 the danger of animals of different species (foxes, raccoon dogs, neglected dogs and cats) as reservoirs and spreaders of the rabies virus has been identified. It is revealed that in this territory rabies is of a natural-focal character. 349 productive, wild, domestic and exotic animals were examined. The final diagnosis of rabies infection was established in 45 animals (12.9%), of which raccoon dogs and foxes were 80.0%, dogs -11.1%, cats - 6.8%. As a result of the analysis of cases of rabies among foxes and raccoon dogs in the Novgorod region, a tendency to an 8-year cycle of epizootic upsurge in the rabies infection in the wild has been revealed. Due to the fact that severe epidemic consequences can not be ruled out on the territory of the Novgorod region, it is necessary to carry out active work on regulating the number of wild carnivores and their immunization with an oral vaccine; carry out measures to eliminate the vagrancy of dogs and cats in the settlements of the region.

The analysis of the epizootic situation shows that over the last 10 years, the country allocated 12 nosologic units of infectious diseases of birds. The etio- Сероварианты E.Coli, logical structure of the causative agent of colibacillosis. The presence in the Republic more than 30 serovariants E. coli. The most widely used in poultry farms have serovariant О1, О2, О78, О26, О15.

For the agro-industrial complex, veterinary and sanitary measures are very important, it is impossible to effectively prevent and eliminate infectious diseases of animals, including birds, without them. Effective disinfection, to a large extent, depends on the availability of highly effective ecologically safe biocides. For this purpose, new disinfectants, methods and regimes of their use are created and tested. Promising in this direction are complex preparations, including washing, disinfecting and degreasing prop erties. The most promising are complex preparations combining washing, disinfecting and degreasing properties. To similar polyfunctional preparations it is possible to attribute «MUK-DM», which is a balanced mixture of surfactants and disinfectants, «MUK-DM» is a viscous, easily mixing liquid (gel) of light yellow color with non-irritating odor. In this paper, the disinfecting effect of the "MUK-DM" preparation on freshly isolated bacterial isolates has been studied. According to the results of laboratory studies, it was found that the most effective biocidal action is the 3% concentration of the preparation at 60 minutes exposure, 1 and 2% concentrations had a disinfecting effect at 180 and 120 minutes exposure, respectively, 0.5% had a disinfecting effect. The results of laboratory tests show that the detergent-disinfectant "MUK-DM" has a bactericidal action against bacterial isolates, which are mixed cultures consisting of rod-shaped and coccoid forms, and can be recommended for carrying out production tests at various enterprises of agro-industrial complex.

For the first time with the program QGIS (version 2.18) data on the isolation and sensitivity to antimicrobials of Salmonella strains, isolated in 2004 - 2016 in the territory of Leningrad region from the sick, the died and slaughtered productive animals, products of animal origin and feed were analyzed.

In Russia, the epizootic situation of rabies has remained tense over the past decades. The main role in the spread of rabies belongs to wild carnivores, neglected dogs and cats. The aim of the work is to evaluate preventive measures against rabies with the help of oral vaccines among wild and neglected carnivores in the Novgorodsky district and the Novgorod regionPreverntion of rabies among wild carnivorous and neglected animals was carried out by placing the oral vaccines "Rabivak-O / 333" and "Oral-Rabivak" produced by Pokrovsky Plant of Biopreparations on the territory of the hunting area of the Novgorod region and in the Novgorod region in urban and rural dumps, visited by wild and domestic carnivores. Rabic prophylaxis among wild carnivores, as well as neglected dogs and cats, carried out in the Novgorod region and the Novgorod region in the period 2008 -2015. with the help of domestic oral vaccines "Rabivac-O / 333" and "Oral-Rabivac" showed their 70% efficiency, but only if it is systematically annualized twice a year. It is necessary to cooperate with the state veterinary and medical services of the Novgorod region in terms of correcting the system of anti-rabies preventive measures in the following areas: 1) reducing the density of populations of foxes and raccoon dogs in all disadvantaged areas, 2) eliminating the neglect of dogs and cats, increase of their vaccine protection level, obligatory preventive vaccination not only of animals in wild fauna, but also of domestic animals if there is a risk of their infection, to create buffer zones around large settlements.

Despite previous researchers provided complete description of helminths, those images fail to demonstrate some anatomical features; spicules, guber-naculums, all 14 ribs; perils of cephalic pole crown and natural color of helminthes [6; 9]. For the purposes of study of helminths, by applying K.I Skrabin’s methodology, in 2014-2015, the full helminthology dissection of bowels of 30 fallen and cut sheep of different age at two southern regions of the Republic of Azerbaijan - in Astara where by sheep breeding takes place on invariable basis and foothill has been conducted. The microscopy study of collected helminths reveals clearly distinctive features Chabertia avina Oesophagostomum coumbianum and Oe.venulosum. It is the first time, visualizing of gubernaculums (Ch. avina, Oe. venulosum), spicules of helminths in different positions (Oe. venulosum) and all 14 ribs of bursa was achieved. Demonstration of the natural color of helminth (light yellow) was also succeeded. Spicules depending on their physiological condition may be situated inside the bursa or coming out of it. In all studies conducted on the samples, it has been concluded that in the helminths with neck papillae, the bursal papillae is absence, or vice-versa, in helminths with bursal papillae the neck papillae is not noticed ( Ch.ovina, Oe.columbianum, Oe. venulosum). Upon analysis of the literature, it has been concluded that these resources fail to demonstrate the full image of morphological specifics of separate helminths [6; 9]. At the images provided by the previous researchers, spicules Oe. columbianum are featured from inside of the helminths only [9,c. 454; 6, c, 71; 1, c. 196], as well as in all resources the spicules Oe. venulosum are not featured at all [9, c. 460; 6, c. 73]. No other references demonstrating other images of helminths different to those initially described by famous scientists Qudey and Rensom were identified in research sources [9, c. 454, 460, 464; 6, 71, 73; 1, c. 196]. It shall be noted that these images have been nomading through sources from many years. Accordingly, on the basis of aforementioned, it is considered important to provide a more comprehensive image and description of morphological structure of helminths studied. The provided image allows without any difficulties to determine the type category and to achieve an accurate diagnostics of the highlighted helminthes.

The aim of the work is to investigate the nature of influence of thyroid hormone at blood sample from the bitches on changes in the staging and duration of the sexual cycle, on the development of incomplete cycles (anovulatory, alibid, anestral, and areactive) and on the maturation of eggs (ovum) in bitches. This research is current because a large proportion of the causes of infertility in dogs and damages of their owners and breeders in problems of the formation of immature, non-viable eggs and the violation of the staging of sexual cycle in bitches. At this work, the functions of thyroid hormones, the nature and significance of the stages of the sexual cycle. Our research shows that the change in the content of thyroid hormones in the blood of the bitch has a direct effect on both the duration and the usefulness of the stages of the sexual cycle. The level of total thyroxin in the blood of the first test group was 11.2±0.9 nmol/l, in the second 4.15±0.35 nmol/l, in the third 6.95±0.85 nmol/l and in the fourth 23,95±7.75 nmol/l. The level of free thyroxine in the blood of the first test group was 8.75±0.45 nmol/l, the second 7.25±2.25 nmol/l, the third 8.9±1.6 nmol/ l and at the fourth 10,75±1.25 nmol/l. The indicators of droplets detector of the DRAMINSKI company for dogs in the stage of anestrus should fluctuate within 80-100 units, if the indices are equal to 100-250 units, then the bitch is diagnosed as infringement of a sexual cycle (inflammatory reaction or hormonal dysfunction). The research is curious not only to practicing veterinarians and scientists, but is also recommended for breeders and dog owners, counting on a favorable course of pregnancy and obtaining a healthy viable puppies.

Modern stage of dairy cattle husbandry development requires multifaceted approach to animal upkeep on dairy farms, including not only hygiene and feeding but also preventive treatment of various visceral diseases. Ketosis is one of the most common non-communicable disease attributable to high yielding cattle. Ketosis usually causes several negative consequences. The most important ones are: yield reduction, lower body resistance, exhaustion, prolonged recovery period after calving, quality of colostrum is poor (the content of immunoglobulins is low), morbidity and mortality of calves in the neonatal period are large. That leads to a higher cull rate, reduced operational life span (around 2-3 lactations), and reduced amount of expected offspring. Kexxtone boluses administration during gestation period has been registered to have a positive effect on cow health condition during lactation period. The amount of ketone bodies in blood does not exceed the amount of ketone bodies in blood of healthy animals. That indicates normalization of energy balance after calving.

The article presents the results of a biochemical study of the blood of young cattle, prone to the development of rickets. As you know, this disease remains relevant at the present time, despite numerous studies in this direction. In many regions of our country the problem of rickets is particularly acute, to such regions is the Leningrad Region. This is due, first of all, to the almost universal transition to year-round stabling of animals, as well as to poor natural insolation in our region. We formed two groups of calves for 10 animals aged 3-3.5 months - experimental and control. During the experiment, the test group calves were administered vitamin D3 in the form of the drug "Akvadetrim" (active substance -cholecalciferol) at a dose of 15 000 units every other day for five weeks. The drug was administered voluntarily by mouth along with a piece of bread. Calves of the control group did not receive vitamin preparations. All calves were examined before the beginning of the experiment, blood from the jugular vein was also selected for the study on the following parameters: the concentration of total calcium, ionized calcium, inorganic phosphorus. A laboratory study showed that the calves' blood indices were not significantly different at the beginning and at the end of the experiment. We can conclude that the study of the blood of calves with subclinical rickets is of little informative, which is associated with the peculiarities of calcium and phosphorus homeostasis. Constants of blood are maintained by the body in sufficiently rigid limits until the last moment.

Diseases in young cattle, such as indigestion or bronchopneumonia are directly dependent on the correct delivery process, assistance during it and reception of the newborn in the calf nursery (cleaning and umbilical cord treatment) and one of the most important factors- correct and timely colostrum feeding. High-quality colostrum fed to a calf in the first 30 minutes after birth contributes to suffi cient strength of colostral immunity, and, consequently, high resistance of the organism in adverse conditions. In the first 5-10 days, calves are most susceptible to diseases. Life-threatening respiratory and digestive system disorders can occur. This can lead to a slowdown in growth, the death of young animals, and this will cause natural economic damage to agriculture. In this regard, it is very important to learn how to identify the primary causes of diseases, as well as find ways to prevent them.

The literature data on the use of immunomodulators of synthetic origin from the group of thymomimetics are present in this article. It is noted that peptide bioregulators have found wide application in surgical practice in human medicine while information on their use in veterinary medicine is limited to particular reports. It is showed that although the presented data indicate positive results of their application they do not give a sufficiently complete answer to the question of treatment tactics in regard to the beginning of bioregulatory therapy. In the experiment on white mice using an aseptic cutaneous-muscular wound model, the diversified wound healing effect of the immunomodulator RV-2 was demonstrated in correlation to the method of application of the drug, the severity of the lesion, the size of the wound defect and the onset of bioregulatory therapy. It is shown that for slight injuries taking into account the diminution of the area and wound healing rate it is preferable to localize the immunomodulator 24 hours after the wounding while intramuscular injection 24 to 120 hours after was inferior to the control group on these indicators. With more extensive wounds (an area 4.5-4.8 times larger), it is effective to perform preoperative drug treatment intramuscularly daily for five days, which reduces the duration of recovery compared to the control group by 1.9 days - from 18.7 ± 0,80 to 16.8 ± 0.80 days with a higher wound healing effect during the first 10 days. Use of the immunomodulator RV-2 120 hours after modeling of the wound has similar mechanism of ac tion. Local treatment of wound defect is ineffective.

The carried out researches at surgical clinical examination showed that surgical diseases of cows occupy a small percentage of the total incidence among the monitored animals of milking flocks in the suburban farms of the city of St. Petersburg. These pathologies cause significant damage to livestock farms because of the culling of diseased animals in the case of failure to take urgent preventive measures and not to eliminate the identified shortcomings. Cows often develop limb injuries - arthritis, tendinitis and tendovaginitis, bursitis, bruises and fractures, tendon ruptures and hoof injuries. Cows with stabled, tethered, uncontrolled content are more often exposed to them. Especially those animals that are kept in a room with latticed floors, on which there are burrs, sharp ribs or exposed fixtures, as well as floors installed on a level. Burrs and armature injure limbs, and a different level of sex makes the load on the hoof uneven, which leads to hoof disease, inflammation of the tendons and joint damage. To prevent injuries to cows, the floors in the cowshed must be flat, smooth and dry. In small farms they can be made of wood or expanded clay concrete. Latticed floors are convenient for manure cleaning, but it is better to make a grate from wood or foamy concrete with a heat-insulating layer. Every 2-3 months of cows with stall content must be chased along the corridor to determine if there are injured animals. Lame or cautious cows need to be examined and treated. To prevent diseases of the distal part of the limbs and hoofs, hoofs must be cleared in time. Clearing is carried out regularly every 3-4 months and necessarily - before pasture on the pasture.

Castration, like any surgical intervention, is accompanied by changes on almost all levels of immunity - macrophage-phagocytic, humoral and cellular, which does not exclude the possibility of postoperative complications. In experiments on two groups of piglets (control and experimental ones, n = 4 in each), two treatment regimens of post-castration wounds were tested - the baseline and experimental ones - with the inclusion of the immunomodulator RV-1 from the group of natural compounds on an alcohol basis, which is a complex balanced composition of biologically active substances. Studies have shown that the local application of the immunomodulator RV-1 in combination with streptocid and “Fortidin-Spray” stimulates the process of tissue regeneration, accelerating the healing rate of the wound. Thus, the dynamics of the area and the percentage of its decrease, the rate of wound healing in the experimental group compared to the control group during all the observation days were more intensive. The most pronounced differences were registered in the seven to thirteen-day period (P< 0,05). The indices of the area decrease in the experimental group had a reliable character (P< 0,05 - 0.001., in the control group in most cases they tended to it. The use of the immunomodulator RV-1 contributed to a reduction in the wound healing time by 2.5 days - up to 14.75 ± 0.48 days compared to 17.25 ± 0.85 in the control. It is shown that the preparation is also growth-stimulating. An assumption is made about the prospects of local immunocorrection for other operative interventions in animals.

The aim of the work was to establish antioxidant and hepatoprotective action of Emicidine on dogs with hepatitis. The object of research were males (n=50) aged 2 to 10 years. They studied biochemical parameters and intensity of iron-induced chemiluminescence of blood serum. It was found that the inclusion in the treatment regimen of hepatitis In dogs emitsidina promotes correction of carbohydrate and protein metabolism, lower blood concentrations of bile acids and alkaline phosphatase, inhibition of free radical oxidation processes and the development of oxidative stress.

Modern toxicology has a lot of information about the toxicity of many substances for living organisms. Acute and chronic toxicity of many inorganic, organic substances, as well as their mixtures of natural or artificial origin, have been measured by various methods. However, today the question of the toxicity of the internal environments of the organism remains open. A priori it is believed that blood serum and extracts of animal organs are not toxic to organisms of the same, and other animal species. In the present work, the toxic reactions of infusoria Paramecium caudatum and Colpoda steinii have been studied for the presence of healthy and sick broiler chicken in their environment. A correlation between serum toxicity and the clinical state of patients was established, the dynamics of changes in serum toxicity from the intensity of the developing pathological process in chickens infected with the Newcastle disease virus was studied. "Paramecia" reaction was studied as an integral indicator of the clinical state of the organism in the occurrence of pathological processes of different etiology. On the basis of the conducted studies, a method for measuring the toxicity of the body's internal environments has been proposed and the norm of the toxicity index of blood serum of broiler chickens for infusorians has been established.

For the first time on the basis of complex studies the zooveterinary expediency of the developed biological preparations Prevention-N-A and Prevention-N-E in beef production technology for the realization of bioresource potential of meat qualities of Black Motley bull-calves was scientifically and experimentally proved. Activation of the growth and development of bull-calves in the periods of growth, rearing and fattening was established against the background of biopreparations, which resulted in higher slaughter and meat qualities of the carcasses and, as a consequence, in a higher yield of valuable cuts. The high quality of meat carcasses by organoleptic, biochemical and spectrometric indicators and, consequently, the safety of the tested preparations was proved. It was found that biological preparations lead to the realization of bioresource potential of the organism due to activation of haemopoiesis, cellular and humoral factors of nonspecific resistance.

The article considers the main changes that are recorded in hypotrophy calves in comparison of their indicators with the data of clinically healthy calves. The study was conducted in one of the farms of the Leningrad Region in 2017. It was noted that in calves-hypotrophics, in comparison with clinically healthy animals, there were signs of slow growth, their mass was on average 3,65 kg lower than in healthy animals. Also, these calves showed a tendency to develop non-communicable diseases, primarily enteritis. On examination, a dull and disheveled coat was noted, often the wool around the anus was contaminated with faeces. The number of erythrocytes in their blood was 23,9 % lower, and the hemoglobin concentration was 12,6 % lower than in clinically healthy animals. The content of leukocytes in clinically healthy calves was on average 13,6 % higher than in experimental calves, and the hematocrit value was 10,3 % higher. The rate of erythrocyte sedimentation in calves of all groups was approximately the same and on average this index was 1,1 mm/h. On the 14th day from the start of treatment in animals of I and II experimental groups, positive dynamics of some blood parameters were observed, but they were of an unreliable nature. Thus, in the calves injected with "Gabivit-Se", the number of red blood cells increased by 10,7 %, while in animals that used "Selemag" by 8,0 %, the concentration of hemoglobin in the blood of the experimental calves of group I also increased by 7,9 %, and in animals of the experimental group, 6,0 %, in comparison with the initial values. When analyzing such indicators as hematocrit and ESR, no significant changes were noted. Based on the above data, it can be concluded that the use of selenium-containing drugs to stabilize the calf-hypotrophic condition is quite effective, especially with a double injection.

This paper presents the results of a study on establishing the effect of a new probiotic feed additive "Baculiform" on the content in the serum of these classes of immunoglobulins Ig A, Ig M, Ig G and intracellular enzymes alanine aminotransferase (ALT) and aspartate aminotransferase (AST). Held scientific - production experience and the results obtained here showed that the inclusion of probiotic feed additive "Baculiform" on the basis of spore-forming bacteria B. subtilis and B. licheniformis part of the basic diet of these the experimental group in doses of 0.2 g/ kg 0.3 g/kg diet contributed to the increase in the serum, compared with the control counterparts, immunoglobulin classes Ig "A" by 9.52% of 14.28% (P<0.01), Ig "M" - by 6.66% and 10.00 % (P<0.05), Ig "G" by 7.52% and 8.83% (P<0.05) On the background of the use in the diet experienced birds tested probiotic feed additives, certain changes occurred and by intracellular enzymes ALT and AST. While there was a slight decrease in the serum experienced these compared to the intact bird ALT on average by 2.69% and 2.56%. Similar patterns of a decrease in the serum experienced these, in comparison with analogues in the control and AST levels, on average of 2.63% and 1.43%.

Realization of high genetic potential of Holstein cows’ milk production (10-12 thousand and more kg of milk per cow), good reproductive abilities, longevity, depends on the full value of feeding during of their preparation for lactation and, especially during the first stage of lactation. Balanced feeding during the first stage of lactation could realize high milk production. With a significant imbalance, especially with energy and protein, the productivity for lactation remains unrealized. Even if the ration is carefully balanced during the remaining months of the lactation, the loss of productivity cannot be restored. The imbalance of ration during the first period of lactation leads to a decrease in the function of reproduction. In order to control the full feeding of the heifers and the first-stage cows during the first stage of lactation, the protein level, the parameters of carbohydrate-fat and vitamin-mineral metabolism in serum are determined.

Feed additive «Primerovskaya» was developed by a group of authors as corrective feed Supplement for use in critical periods of development of young farm animals and poultry. The value of the feed additive with animal protein is determined by the content of raw protein and the percentage of amino acids. Knowledge of the amino acid composition of the feed additive allows not only to accurately calculate the diet taking into account its actual nutritional value, but also to use feed products that meet the nutritional requirements of a particular age and sex group, which significantly reduces costs in production conditions. Based on the analysis of the research carried out by the authors, they conclude that the feed additive «Prinarovskaya» meets the norms of nutrition and safety, it is advisable to produce and use it in animal husbandry and poultry farming as a corrective feed additive in critical periods of young growth.

The primary purpose of my thesis is to research the particularities of the blood circulation in the digits of the thoracic limb of the Black-Motley cows. The research methods used in this study included vaso-roentgenography.The infusion into arterial line was conducted through the medial palmar artery. It was established that the arterial supply of the digits of the forelimb in the Black-Motley cows is from the three great vessels. The arteries supplying the third digit are the well-developed third common palmar digital artery and lateral branch of the special third medial palmar digital artery, as well as the underdeveloped special dorsal third digital artery. The arteries supplying the forth digit are the well-developed forth common palmar digital artery and lateral branch of the special medial forth palmar digital artery, as well as the underdeveloped special dorsal forth digital artery. Considering the development of these great vessels, we find the dorsal approach for surgical treatment of the digits in this breed most expedient.

The problem of rational use of protein forage and protein metabolism in cows with high productivity is very relevant. To monitor the full feeding of highly productive cows, zootechnical, clinical and biochemical methods are recommended. With the purpose of an auxiliary means of control over the full value of feeding in cows with a productivity of more than 9,500 kg of milk, urea in blood and milk was studied in lactation and dry-period stages. Biochemical blood tests were performed characterizing the state of metabolic processes in the organism of highly productive dairy cows by lactation stages while feeding them with adaptive food rations under conditions of industrial milk production technology.

Human cadaver material for the study was delivered to the Department of anatomy of animals FGBOU VO "Saint-Petersburg state Academy of veterinary medicine" from a pig-breeding complex "Idavang agro" D. Nurma, Tosnenskiy district of Leningrad region. The age of pigs ranged from 1 to 30 days of birth by age groups: 1-7 days; 10-17 days; 20-28 days. Breeds of pigs - Landrace and Duroc. Upon examination of the lungs determined by the number of shares, size, degree of development of connective tissue stroma and the working tissue of the parenchyma, distinctness of segments and lobes of the lung. The fresh and frozen lungs of pigs of both breeds received from the killed animals subjected to thin anatomical preparation. A saggital incision from the tip to the base of the lungs was used, followed by dissection. Linear parameters of lungs were determined by electronic caliper model "Tamo professional" with a scale of division of 0.05 mm, made in the USA. The absolute mass of the liberated lungs was determined on the electronic scales "CAS 0,2 HFS". Thus, came to a conclusion that to age group of newborn pigs of 10-14 days of breed Landrace and Duroc, the absolute weight of a lung as a whole increases on the average 1,6-1,7 times in comparison with newborns of 1-7 days. In newborns 20-28 days weight of the lung increases in 1,5-1,6 times in comparison with newborns 10-14 days. Consequently, the lungs of newborn piglets of Landrace and Duroc have anatomically well-formed lobes. Increase lung according to age groups occurs evenly and, as a rule, the mass is dominated by the average and caudal proportion.

Cow's milk has a mild pleasant smell, which is hard to describe; the taste is pleasant, slightly sweet and salty, which is caused by the chemical composition. Odorous carbonyl compounds is one of the main substances involved in the formation of odor, taste and flavor of milk. The strength and character of the odor of these compounds depend on their structure and concentration. The reasons for the presence of aldehydes in milk can be different, for example: the manifestation of the activity of carboxylase milk, which catalyze the decarboxylation reaction of many acids; the use of feed treated with formaldehyde; the use of formalin (40% formalde hyde solution) as a preservative of milk for longterm storage in natural conditions. Find simple ways to get new sorbents for sorption preconcentration of microcomponents and for the chromatographic separation remains an urgent task. Sorbents on the basis of aluminum oxide can be an alternative to the currently used for the separation and concentration of various substances organopolymers and silica sorbents. The aim of this work was to develop a method that enables high Express, precision and reproducibility to evaluate the content of formaldehyde in the vapor of milk. Method had to be easy to use and not too expensive. The article discusses a new method for the determination of formaldehyde in milk flavor. The essence of the method lies in the fact that the definition is carried out using nanostructured film of aluminum oxide (POA) with hexagonal structure of size 7'30 mm as a sorbent of formaldehyde from a gas environment to reduce the luminol-dependent chemiluminescence in a system generating hydroxyl radicals in the presence of formaldehyde. The conditions of film synthesis of nanoporous aluminum oxide is determined. The proposed method for the determination of formaldehyde in milk flavor is characterized by ease of preparation of samples for study, high reproducibility and relatively high speed of the analysis.

On the basis of the St. Petersburg State Academy of Veterinary Medicine, we carried out the research on the new feed mix "Pular" with the feeding of broiler chickens and its’ effect on the biochemical status of the blood of birds. For the experiment, 3 experimental groups of broiler chickens "Ross-308" were formed according to the principle of analogues (cross, age, living weight, development), 10 heads in each. Conditions for maintenance and feeding for all groups were the same. The main ration of the chickens was full-fat PK-6 feed mix, the chickens of the second experimental group additionally received 60% of PK-6 and 40% of the new feed additive Pular in addition to the feed mix, and third group - 10% of PK-6 and 90% of the new feed additive Pular. The experiment was conducted during 3 weeks. An increase in the total protein in the blood serum was detected while analyzing the biochemical parameters of blood, which indicates the activation of protein metabolism, an increase in the amount of calcium and phosphorus, indicates better absorption by the body, an increase in cholesterol in the second and third experimental groups by 30, 42 - 37.74% in comparison with the control indicates an increase in the level of metabolic processes, an increase in the concentration of the ALT enzyme by 4.18% and a decrease in the AST content by 19.73-22.95% in the second and third experimental subjects groups in comparison with contacts. The increase in the level of diene conjugates, dienketones in the blood serum of broilers receiving the feed "Pular" indicates activation of the processes of free radical oxidation, a decrease in the amount of MDA indicates a faster evacuation of harmful metabolic products and effective work of the antioxidant system of protecting the body of the bird. A study of the biochemical composition of the blood showed that the inclusion of the feed additive "Pular" in the broiler diet did not adversely affect the bird's organism, all the blood indicators were within the limits of the referent amounts.

In daily practice veterinarian when working with smaller animals often found with broken bones, this applies in particular to the bones of the pelvic limb. In the treatment of these pathologies, the most effec-tive result is osteosynthesis. It is extremely difficult to carry out this surgical intervention without clear knowledge of topography of vascular and nerve bun-dles. Therefore, the aim of this work is to determine syntopia blood vessel region of the foot cat’s home and give them a morphometric feature. Ten corpses of cats of different breeds served as a material for carrying out this work. The study used methods of fine anatomical dissection and waterin-tensive. The suspension of lead minium in turpentine with ethyl rectified alcohol (lead minium 10%, live turpentine 30-60%, alcohol up to 100%) was used as x-ray contrast mass. The injection was carried out by a conventional method through the abdominal aorta. When specifying anatomical terms, the International veterinary anatomical nomenclature of the fifth edi-tion was used. As a result of the conducted research it was es-tablished that the main sources of blood supply to the foot area in the domestic cat are cranial tibias artery and safen's artery. At the level of all homody-namic parts of the foot, these highways and their branches anastomose with each other, forming the pathways of collateral circulation. So at the level of the distal end of the tibia they are combined by the lateral and medial ankle arteries. In the field meta-carpi joint unites them salute perforating artery. In the area of distal ends of metatarsal bones, both highways, uniting with terminal branches, form pal-mar finger arteries. The latter are the main vessels in the area of the fingers. Also noteworthy is anastomo-sis located in the distal end of the claw phalanx. Here the axial and neosoviet finger artery form anas-tomosis with the corresponding moralnymi finger arteries. Thus, the obtained data on the possible ways of collateral blood supply to the study area should be taken into account during surgical interventions.

This paper presents study data of “Vigozin” application in broiler chicken; one of the major compound of this supplement is carnitin. The aim of this research was study of “Vigozin” application in broiler chicken and its impact on hematological and immune-biochemical blood profiles during growing period. Target of research was “KOBB-500” cross broiler-chickens in the age of 5, 7, 12, 19, 28, 36 and 46 days. During research 4 groups of animals were formed. First group is a control group. Second group is an experimental group; broiler chickens received “Vigozin” supplementation diluted with water (1 ml supplementation per 1 l of drinking water) twice - first during 3 days consecutively with 8 days inter-val. Third group is an experimental group; broiler chickens received “Vigozin” supplementation di-luted with water (1 ml supplementation per 1 l of drinking water) during first 3 days. Fourth group is an experimental group; broiler chickens received “Vigozin” supplementation diluted with water (1 ml supplementation per 1 l of drinking water) during first 5 days. During study hematological and immune-biochemical blood profiles of all groups was assessed. The study outcome reveal the best “Vigozin” application impact in next dosage scheme - twice - during first 3 days and on 13th day. This dosage scheme allows offspring metabolism normalization hepatic function support, that results in broiler chickens mortality reducing by 2,3%. IN-TRODUCTION Poultry farming have an important part in animal production productivity.